![]() The next dose should be taken as scheduled. If a patient misses a single dose of memantine hydrochloride tablets, that patient should not double up on the next dose. Memantine hydrochloride tablets can be taken with or without food. The dosage shown to be effective in controlled clinical trials is 20 mg/day. The minimum recommended interval between dose increases is one week. The dose should be increased in 5 mg increments to 10 mg/day (5 mg twice daily), 15 mg/day (5 mg and 10 mg as separate doses), and 20 mg/day (10 mg twice daily). The recommended starting dose of memantine hydrochloride tablets is 5 mg once daily.
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